Mesenchymal Hamartoma of the Liver and DICER1 Syndrome

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Mesenchymal hamartoma of the liver.

Mesenchymal hamartoma of the liver is the second most common benign liver tumor of childhood. Ultrasonography demonstrates a cystic lesion that may be very large. Computed tomographic scan will further establish the location and its relationship to vascular anatomy. Most will be amenable to gross total resection with clear margins. To illustrate the radiological and gross operative features, we...

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Mesenchymal Hamartoma of Liver in a Neonate

Introduction: Mesenchymal hamartoma of liver (MHL) is the second most common benign liver tumor in children. This tumor typically presents as a large benign cystic mass, solid or mix in children less than three years. Prenatally, it may grow quickly to an abnormal size that may lead to death or hydrops. Prenatal suspicion arises by increasing maternal serum α-FP or HCG and polyhydroamnious and ...

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Solid mesenchymal hamartoma of the liver in adult.

This paper presents an unusual solid mesenchymal hamartoma of the liver (MHL) in adult. A well defined solid mass in the left lobe of the liver was found in a 57-year-old female. Preoperative radiologic examinations demonstrated solid mass with multifocal calcifications abutting the gallbladder. By light microscopy, the lesion was composed of dense fibrous stroma with hyalinization, bile ducts ...

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Mesenchymal hamartoma of the liver--report of an unusual case.

An 8 year old girl presented with gross hepatomegaly, anaemia and pyrexia unresponsive to antibiotics. At laparotomy a cystic mass 19 cm in diameter was found arising from the liver. The cyst contained 2.4 litres of changed blood and an abscess cavity filled with thick pus was present in the cyst wall. Histological examination showed the appearances of a mesenchymal hamartoma of the liver, a ra...

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Mesenchymal Hamartoma of the Liver: Complete Excision Always Necessary

Mesenchymal hamartoma (MH) is not an uncommon tumor of the liver in the age group of 2-10 years. It is the second most common benign liver tumor in children. Previously considered a developmental anomaly, newer insights into other theories of origin including toxic-metabolic, ischemic, and a true neoplastic process are in progress. Previous understanding of a purely benign nature of the tumor i...

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ژورنال

عنوان ژورنال: New England Journal of Medicine

سال: 2019

ISSN: 0028-4793,1533-4406

DOI: 10.1056/nejmoa1812169